…There are many more types of nucleases than synthetic enzymes, and they play a variety of roles necessary for life. Nucleases are broadly divided into deoxyribonucleases (DNases) and ribonucleases (RNases) according to the type of substrate (DNA or RNA). In addition, there are various types of cleavage, such as those with high specificity for the base sequence at the site of cleavage of nucleic acid (restriction enzymes) and those with almost no specificity, those that cleave sequentially from the end of the nucleic acid molecule (exonucleases), those that cleave in the middle (endonucleases), those that cleave double-stranded nucleic acid, and those that specifically cleave single strands. … *Some of the terminology that mentions "RNase" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…核酸分解酵素の種類は合成酵素よりもはるかに多く,生命維持のために必要な,きわめて多様な役割を果たしている。 核酸分解酵素は,まず基質の種類(DNAかRNAか)によって大きくデオキシリボヌクレアーゼ(DNase)とリボヌクレアーゼ(RNase)に分けられる。また,核酸の切断される位置の塩基配列に高い特異性のあるもの(制限酵素),反対にほとんどないもの,また核酸分子の末端から順々に切断を行うもの(エキソヌクレアーゼ),中間を切断するもの(エンドヌクレアーゼ),あるいはまた二本鎖の核酸を切断するもの,一本鎖を特異的に切断するものなど,その切断の様式はさまざまである。… ※「RNase」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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