Nucleophilic substitution

Japanese: nucleophilic substitution（英語表記）nucleophilicsubstitution

…It is also called a substitution reaction. There are two types of substitution: nucleophilic substitution (abbreviated as S _N ) and electrophilic substitution (abbreviated as S _E ). The former, S _N , is a reaction in which a nucleophile (N ^－ ) attacks a molecule (M-X) that has an atom or group of atoms (X) that is easily substituted, expelling X (Equation (1)). …

From [Organic Chemical Reactions]

...The most common classification is one that combines this with the distinction between substitution, elimination, and addition.
[Nucleophilic substitution reaction]
A reaction in which a nucleophilic reagent (Nu:) attacks a positively charged carbon atom of a substrate and replaces the bonded atom or group is called a nucleophilic substitution reaction. The atom or group that is displaced is called a leaving group (abbreviated as L:).

*Some terminology explanations that mention "nucleophilic substitution" are listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

Japanese:

…置換反応とも呼ばれる。置換には求核置換反応nucleophilic substitution(略称S_N)と求電子置換反応electrophilic substitution(略称S_E)の2種類がある。前者S_Nは求核試薬nucleophile(N^－)が置換されやすい原子または原子団(X)をもつ分子(M－X)を攻撃して，Xを追い出す反応をいう(式(1))。…

【有機化学反応】より

…これを置換，脱離，付加の区別と組み合わせた分類が最も一般的である。
［求核置換反応］
　求核試薬Nu：が正電荷を帯びた基質炭素原子を攻撃し，結合している原子または基と置換する反応を求核置換nucleophilic substitution反応という。追い出される原子または基を脱離基leaving group(L：と略記)という。…

※「nucleophilic substitution」について言及している用語解説の一部を掲載しています。

出典｜株式会社平凡社世界大百科事典第２版について | 情報

<<: Nucleophilic reagent

>>: nucleoplasm