Osteoarthritis deformans endemica

...A disease that causes bone deformation discovered in eastern Siberia by the Russian NI Kashin and later detailed by the Beck couple EV Beck and A N Beck. It is an endemic disease that was also seen in northeastern China and northern Korea. It is also called endemic osteoarthritis deformans endemica. Early lesions in children during the growth period are characterized by degeneration of the epiphyseal cartilage and swelling of the joints. In severe cases, it is said to cause stunted growth, degeneration of salivary gland epithelial cells, and abnormal secretion of salivary gland hormones. ...

*Some of the terminology that refers to "osteoarthritis deformans endemica" is listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

…1861年東部シベリアでロシアのカシンN.I.Kashinによって発見され，その後ベック夫妻E.V.Beck,A.N.Beckによって詳述された骨変形を起こす疾患で，中国東北地方，朝鮮北部にもみられた地方病。地方病性変形性骨関節炎osteoarthritis deformans endemicaともいう。成長期の子どもの骨端軟骨の変性や関節の腫張などが特徴的な初期の病変で，重症になると，身長の伸びが止まったり，唾液腺上皮細胞の変性，唾液腺ホルモンの分泌異常もひき起こすといわれる。…

※「osteoarthritis deformans endemica」について言及している用語解説の一部を掲載しています。

出典｜株式会社平凡社世界大百科事典 第２版について | 情報