...A monolayer culture is when cells adhere to the bottom of the culture vessel and grow by extending their cytoplasm. Most normal cells, except mature hematopoietic cells, grow in this manner. Normal cells grow to cover the bottom of the vessel and when they come into contact with each other, they undergo contact inhibition, which means that they no longer divide. If some of the cells are then removed and transferred to a new vessel, they will begin to divide and grow again. ... *Some terminology explanations that mention "contact inhibition" are listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…細胞が培養器内で底面に接着し,細胞質をのばして増殖するのが単層培養monolayer cultureで,成熟した造血細胞以外の大部分の正常細胞はこの形式で増殖する。正常な細胞は,増殖して培養器底面をおおいつくし,互いに接触するようになると接触阻止現象contact inhibitionを生じて,それ以上は分裂しなくなる性質をもっている。このとき,細胞の一部を取り出して新しい培養器に移してやると,細胞は再び分裂を開始して増殖する。… ※「contact inhibition」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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